Gamma-ketoacid dipeptides as inhibitors of caspase-3
US6225288A · kind A · utility
7Cited by
1References
14Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 16, 2000 |
| Grant date | May 1, 2001 |
| Priority date | — |
| Expiry date | Mar 16, 2020 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C323/59
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Compounds represented by formula I: ##STR1## as well as pharmaceutically acceptable salts, esters and hydrates thereof are disclosed along with pharmaceutical compositions and methods of treatment. The compounds are useful as inhibitors of caspase-3, which is implicated in modulating apoptosis.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.