Primary intermediate in oxidative hair dyeing

US6228130A · kind A · utility

Assignee

• Bristol-Myers Squibb Company · US

Inventors

• Mu-Ill Lim · Trumbull, US
• Linas R. Stasaitis · Fairfield, US
• Yuh-Guo Pan · Stamford, US
• Michael Wong · Leven, GB

Key dates

• Filing date: Nov 3, 1998
• Grant date: May 8, 2001
• Expiry date: Nov 3, 2018

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C215/68
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

5-Nitroisatin is reacted with sodium hydroxide to produce an .alpha.-keto acid sodium salt that is reduced with borane-tetrahydrofuran complex and then hydrogenated to produce 1-(2,5-diaminophenyl)ethylene glycol, a novel compound useful as a primary intermediate in the production of oxidative hair dyes.