Stable factor VIII/von Willebrand factor complex

US6228613A · kind A · utility

Assignee

• Baxter Aktiengesellschaft · AT

Inventors

• Bernhard Fischer · Wien, AT
• Artur Mitterer · Orth an der Donau, AT
• Friedrich Dorner · Wien, AT
• Johann Eibl · Wien, AT

Key dates

• Filing date: Nov 6, 1998
• Grant date: May 8, 2001
• Expiry date: Nov 6, 2018

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y10T436/25375
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

There are disclosed a stable factor VIII/vWF-complex, particularly comprising high-molecular vWF multimers, being free from low-molecular vWF molecules and from proteolytic vWF degradation products, as well as a method of producing this complex.