Synthesis of hydroxamic acid derivatives
US6228988A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jun 9, 1999 |
| Grant date | May 8, 2001 |
| Priority date | — |
| Expiry date | Jun 9, 2019 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02P20/55
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention describes processes for preparing desired synthetic products that comprise a covalently bonded hydroxamic acid group --CONHOH by forming a mixture of a liquid reaction medium and a solid phase reaction product that carries a plurality of moieties of formula (A1) or (B1): ##STR1## where X is a residual, non-hydroxamate partial structure of the desired synthetic product, P.sub.1 is hydrogen or an amino-protecting group, P.sub.2 is hydrogen or a hydroxyl protecting group, and the bond designated (a) covalently links the moieties (A1) or (B1) to the residue of a solid substrate; by cleaving the bond designated (a) in the resultant mixture; and by separating the resultant liquid reaction phase from the resultant reaction solids to recover the desired synthetic product.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.