Process for preparing quinolone- and naphthyridone- carboxylic acids and esters thereof

US6229017A · kind A · utility

Assignee

• BAYER HEALTHCARE LLC · DE

Inventors

• Norbert Lui · Odenthal, DE
• Hans Panskus · Leverkusen, DE
• Herbert Muller · Bischofswerda, DE

Key dates

• Filing date: Jun 11, 1999
• Grant date: May 8, 2001
• Expiry date: Jun 11, 2019

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D215/56
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

An improved process for preparing quinolone- and naphthyridonecarboxylic acids and esters thereof from benzoyl chlorides and nicotinoyl chlorides, respectively, in which the reaction carried out in the presence of a non-polar to slightly polar solvent without separation of intermediaries that form during the process.