2,7-substituted octahydro-1H-pyrido[1,2-A]pyrazine derivatives as ligands for serotonin receptors
US6231833A · kind A · utility
2Cited by
2References
40Claims
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Key dates
| Filing date | Aug 5, 1999 |
| Grant date | May 15, 2001 |
| Priority date | — |
| Expiry date | Aug 5, 2019 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Substituted pyrido[1,2-a]pyrazines of general formula I; wherein Ar and Ar.sup.1 represent various carbocyclic and heterocyclic aromatic rings; A represents O, S, SO, SO.sub.2, CHOH, C.dbd.O, or --(CR.sup.3 R.sup.4); and n is 0-2, as well as precursors thereto, are ligands for dopamine receptor subtypes and serotonin (5HT) within the body and are therefore useful in the treatment of disorders of the dopamine and serotonin systems: ##STR1##
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.