Composition for controlled and sustained transdermal administration
US6231885A · kind A · utility
Assignee
Inventor
Key dates
| Filing date | Sep 15, 1998 |
| Grant date | May 15, 2001 |
| Priority date | — |
| Expiry date | Sep 15, 2018 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61L15/58
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A patch for transdermal administration of drugs through controlled release system, consisting essentially of: PA1 A) a flexible backing layer; PA1 B) an adhesive layer comprising: PA2 an adhesive pressure sensitive adhesive polymeric matrix, PA2 a cohesion improver, PA2 a tackifier agent, PA2 a combination of permeation enhancers consisting of a first component which is a saturated fatty acid or fatty alcohol represented by the formula CH.sub.3 --(CH.sub.2).sub.n --COOH or CH.sub.3 --(CH2).sub.n --CH.sub.2 OH respectively, in which n is an integer from 6 to 16, and of a second component which is a monounsaturated fatty acid or fatty alcohol represented by the formula CH.sub.3 --(C.sub.n H.sub.2(n-1))--COOH or CH.sub.3 --(C.sub.n H.sub.2(n-1))--CH.sub.2 OH respectively, in which n is an integer from 8 to 22, with the provision that the chain lenght of the first component is different from that of the second component, PA1 C) a protective liner, which is removed at the moment of use.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.