Patent · US Expired

Monoclonal antibodies against leucocyte-specific G protein-coupled receptors

US6232123A · kind A · utility

0Cited by

1References

10Claims

0Family size

Inventors

Martin Lipp · Berlin, DE
Reinhold Forster · Ahrensfelde, DE
Thomas Emrich · Iffeldorf, DE
Ingrid Wolf · Seattle, US
Elisabeth Kremmer · Freising, DE

Key dates

Filing date	Aug 13, 1996
Grant date	May 15, 2001
Priority date	—
Expiry date	Aug 13, 2016

Classification

Technology area (CPC Y)Emerging Cross-Sectional Technologies
CPC primaryY10S435/81
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

The invention relates to monoclonal antibodies against leucocyte-specific G protein-coupled receptors (L-GCR). These antibodies are obtainable by the following steps: (a) introduction of an L-GCR-coding nucleic acid into cells and expression of L-GCR, (b) immunization of an animal with L-GCR-expressing cells of (a), and (c) fusion of spleen cells from the immunized animal of (b) with myeloma cells and production of monoclonal L-GCR antibody-producing hybridoma cells. Furthermore, the invention relates to processes for the production of such antibodies, their use and kits containing the same. In addition, the invention concerns a process for the production of monoclonal GCR antibodies.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.