Composition for improving pancreatic function
US6232288A · kind A · utility
6Cited by
0References
26Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Apr 15, 1998 |
| Grant date | May 15, 2001 |
| Priority date | — |
| Expiry date | Apr 15, 2018 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/22
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides a novel composition comprising a betacellulin protein, or a fragment thereof, which is capable of promoting the differentiation of undifferentiated pancreatic cells into insulin-producing beta cells or pancreatic polypeptide producing F cells. This composition can also improve glucose tolerance in patients and inhibit the growth of undifferentiated pancreatic cells. The composition may further comprise activin and/or other molecules. Methods for treating mammals, including humans, are also provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.