Cyclic hexapeptides with antimicrobial activity
US6232290A · kind A · utility
12Cited by
5References
9Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 22, 1999 |
| Grant date | May 15, 2001 |
| Priority date | — |
| Expiry date | Dec 22, 2019 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This invention relates to new polypeptide compounds represented by general formula (I), wherein R.sup.1, R.sup.2, R.sup.3 and R.sup.4 are as defined in the description or a salt thereof which has antimicrobial activities (especially, antifungal activities), inhibitory activity on .beta.-1,3-glucan synthase, to process for preparation thereof, to a pharmaceutical composition comprising the same, and to a method for prophylactic and/or therapeutic treatment of infectious diseases including Pneumocystis carinii infection (e.g. Pneumocystis carinii pneumonia) in a human being or an animal. ##STR1##
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.