Process for preparing fluorine-containing phenethylamines and novel fluorine-containing .beta.-iminovinyl-and .beta.-iminoethylbenzenes
US6232475A · kind A · utility
2Cited by
1References
8Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 16, 1999 |
| Grant date | May 15, 2001 |
| Priority date | — |
| Expiry date | Dec 16, 2019 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D405/06
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention relates to a process for preparing fluorine-containing phenethylamines which is characterized in that, in a first step, a substituted bromobenzene is reacted with an N-vinylimide in the presence of a palladium catalyst, in a second step, the resulting substituted .beta.-iminovinylbenzene is hydrogenated catalytically and in a third step, the substituted .beta.-iminovinylbenzene obtained in the second step is cleaved. This process also provides access to novel .beta.-iminovinyl- and .beta.-iminoethylbenzenes.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.