Metastasis models using green fluorescent protein (GFP) as a marker
US6232523A · kind A · utility
42Cited by
4References
7Claims
0Family size
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Key dates
| Filing date | Apr 28, 1997 |
| Grant date | May 15, 2001 |
| Priority date | — |
| Expiry date | Apr 28, 2017 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K48/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method to follow the progression of metastasis of a primary tumor, which method comprises removing fresh organ tissues from a vertebrate subject which has been modified to contain tumor cells that express GFP and observing the excised tissues for the presence of fluorescence is disclosed. Vertebrate subjects which contain GFP producing tumors are useful models to study the mechanism of metastasis.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.