Synthetic polypeptides belonging to the hepatitis C virus (HCV) and which can be used especially for detecting the latter
US6235284A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jan 30, 1995 |
| Grant date | May 22, 2001 |
| Priority date | — |
| Expiry date | Jan 30, 2015 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S530/81
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to a polypeptide comprising a peptide sequence belonging to the sequence of the first 62 amino acids of the terminal part of the CORE (or capsid) protein of the human hepatitis C virus (HCV), the polypeptide comprising either an isolated peptide sequence that is composed of the 45 N-terminal amino acids of the core protein, with 1 to 10 amino acids optionally amputated from its N-terminal part and/or its C-terminal part, or an immunogenic sequence equivalent to the peptide sequence and exhibiting immunological cross-reactivity with the peptide sequence towards HCV. The invention also relates to a polypeptide composition, a reagent and a means for the detection of the HCV virus, a process and a device for the detection of anti-HCV antibodies, an immunotherapeutic composition and antibodies directed against HCV.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.