Device and method for making a segmented tubular capsule containing a biologically active medium
US6235303A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Apr 16, 1999 |
| Grant date | May 22, 2001 |
| Priority date | — |
| Expiry date | Apr 16, 2019 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61F2/022
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Method of manufacturing a tubular capsule comprising fiber (11) having a wall delimiting internal compartments (11b) that are isolated from one another, the wall being made from a solution of at least one polymer and the compartments (11b) being full of a biologically active medium, the method comprising the steps of: PA1 coextruding the solution of at least one polymer and the biologically active medium by simultaneously injecting the polymer solution and the biologically active medium through a die (7) of determined dimensions; PA1 interrupting the injection of the biologically active medium at determined points in time to form in the fiber (11) successive compartments (11b) full of the biologically active medium and separated by a solid partition section (11a) consisting only of the polymer solution; PA1 immersing the fiber (11) in a coagulation liquid as it leaves the die (7) so as to initiate early coagulation of the polymer solution around the outside of the fiber (11); and PA1 simultaneously driving the fiber (11) through the coagulation liquid along a determined path.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.