Sorbent method for removal of cryoprotectants from cryopreserved animal cells
US6235463A · kind A · utility
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13References
14Claims
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Key dates
| Filing date | May 6, 1999 |
| Grant date | May 22, 2001 |
| Priority date | — |
| Expiry date | May 6, 2019 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB01D15/00
- WIPO fieldChemical engineering
- WIPO sectorChemistry
Abstract
A method is disclosed for removal of cryoprotectants from preserved suspension of biological cells and tissues. Sorbent materials are used, alone or in combination, to bind the cryoprotectant component of preserved cell suspensions with minimal osmotic stress on the preserved cells. The present method is used to effectively remove the cryoprotectants from cryopreserved cells and tissues prior to their use in transfusion, transplantation, insemination or other applications, with minimal osmotic damage due to cell swelling. Specific devices and methods are described.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.