Fluorescent energy transfer ligand interaction assay on a lipid film
US6235535A · kind A · utility
17Cited by
11References
11Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 24, 1998 |
| Grant date | May 22, 2001 |
| Priority date | — |
| Expiry date | Dec 24, 2018 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S436/829
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
This invention relates to a fluorescence-based immunoassay method for the detection of an analyte, or for the measurement of its concentration in a biological sample. The method is based on the ability of a multivalent analyte to induce aggregation of receptor molecules labeled with a fluorophore, which molecules are anchored to and are freely mobile on a lipid membrane, and thereby cause changes in the fluorescence.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.