Substituted 2-anilinopyrimidines useful as protein kinase inhibitors
US6235746A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Feb 16, 1999 |
| Grant date | May 22, 2001 |
| Priority date | — |
| Expiry date | Feb 16, 2019 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D417/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Compounds of general formula (1) are described: ##STR1## wherein R.sup.1 is a hydrogen or halogen atom or an optionally substituted straight or branched chain alkyl, alkenyl or alkynyl group or a group selected from hydroxyl (--OH), substituted hydroxyl, thiol (--SH), substituted thiol, amino (--NH.sub.2), or substituted amino; PA1 R.sup.2 and R.sup.3, which may be the same or different, is each an optionally substituted straight or branched chain alkyl, alkenyl or alkynyl group; PA1 R.sup.4 is a hydrogen atom or a straight or branched chain alkyl group; PA1 R.sup.5 is a hydrogen atom or an optionally substituted straight or branched chain alkyl, alkenyl or alkynyl group; PA1 R.sup.6 is a hydrogen or halogen atom or an amino (--NH.sub.2), substituted amino, nitro, carboxyl (--CO.sub.2 H) or esterified carboxyl group or a group --X.sup.1 --R.sup.6a where X.sup.1 is a direct bond or a linker atom or group and R.sup.6a is an optionally substituted straight or branched chain alkyl, alkenyl or alkynyl group; PA1 X is a direct bond or a linker atom or group; PA1 R.sup.7 is an optionally substituted aliphatic, cycloaliphatic, heteroaliphatic, heterocycloaliphatic, aromatic or heteroaromat…
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.