Indole derivatives as 5-HT receptor antagonist
US6235758A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jul 23, 1999 |
| Grant date | May 22, 2001 |
| Priority date | — |
| Expiry date | Jul 23, 2019 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D417/14
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A compound of formula (I) or a salt thereof: ##STR1## wherein: PA1 P.sup.1 is pyridiyl; PA1 P.sup.2 is phenyl; PA1 A is a bond or a chain of 1 to 5 atoms optionally substituted by C.sub.1-6 alkyl; PA1 R.sup.1 and R.sup.2 groups are each independently hydrogen, C.sub.1-6 alkyl optionally substituted by NR.sup.12 R.sup.13, C.sub.2-6 alkenyl, C.sub.2-6 alkynyl, cyano, halogen, CF.sub.3, NR.sup.12 R.sup.13, CHO, OCF.sub.3, COR.sup.14, CH.sub.2 OR.sup.14 or OR.sup.14 where R.sup.12, R.sup.13 and R.sup.14 are independently hydrogen or C.sub.1-6 alkyl; PA1 n and m are independently 0, 1 or 2; PA1 R.sup.3 is hydrogen or C.sub.1-6 alkyl; PA1 R.sup.4 is a group of formula (i): ##STR2## in which: PA1 R.sup.6 and R.sup.7 are independently hydrogen, C.sub.1-6 alkyl optionally substituted by one or more fluorine atoms, C.sub.1-6 alkylthio, C.sub.1-6 alkoxy or halogen.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.