Patent · US Expired

Metal-catalyzed arylations of hydrazines, hydrazones, and related substrates

US6235936A · kind A · utility

66Cited by

3References

22Claims

0Family size

Assignee

Massachusetts Institute of Technology · US

Inventors

Stephen L. Buchwald · Newton, US
Seble H. Wagaw · Lake Bluff, US
Oliver Fabian Geis · Berlin, DE

Key dates

Filing date	Feb 26, 1998
Grant date	May 22, 2001
Priority date	—
Expiry date	Feb 26, 2018

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D401/04
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

A method is provided for the transition metal-catalyzed arylation, or vinylation, of hydrazines, hydrazones, and the like. Additionally, the invention provides a conceptually novel strategy, the cornerstone of which is the transition metal-catalyzed arylation or vinylation method, for the synthesis of indoles, carbazoles, and the like. The methods and strategies of the invention may be utilized in standard, parallel, and combinatorial synthetic protocols.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.