Cloning pigs using donor nuclei from non-quiescent differentiated cells
US6235969A · kind A · utility
25Cited by
3References
26Claims
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Key dates
| Filing date | Jul 3, 1997 |
| Grant date | May 22, 2001 |
| Priority date | — |
| Expiry date | Jul 3, 2017 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2517/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
An improved method of nuclear transfer involving the transplantation of donor differentiated pig cell nuclei into enucleated pig oocytes is provided. The resultant nuclear transfer units are useful for multiplication of genotypes and transgenic genotypes by the production of fetuses and offspring. Production of genetically engineered or transgenic pig embryos, fetuses and offspring is facilitated by the present method since the differentiated cell source of the donor nuclei can be genetically modified and clonally propagated.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.