Presentation of hydrophobic antigens to T-cells by CD1 molecules
US6238676A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jul 12, 1995 |
| Grant date | May 29, 2001 |
| Priority date | — |
| Expiry date | Jul 12, 2015 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12P19/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Provided are CD-1 presented antigens, compositions, cells, inhibitors and methods relating to the use of hydrophobic antigen presentation by CD1 molecules, including: PA1 methods for detecting the presence of a CD1-presented hydrophobic antigen in a sample; PA1 methods for isolating such CD1-presented antigens and the isolated antigens; PA1 vaccines containing CD1-presented antigens and vaccination methods; PA1 methods of blocking CD1 antigen presentation; PA1 methods of identifying and/or isolating CD1 blocking agents and the isolated CD1 blocking agents; PA1 methods of inducing CD1 expression; and PA1 T-cells for use in the methods disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.