Ribosome recycling factor (FRR) of Staphylococcus aureus

US6238887A · kind A · utility

Assignees

• The Brigham and Women's Hospital, Inc. · US
• Virus Research Institute · US
• SmithKline Beecham Limited · US
• SmithKline Beeacham P.L.C. · GB

Inventors

• David T Beattie · Boston, US
• Robert L Deresiewicz · Boston, US
• Adrian M Lowe · Watertown, US
• Michael Arthur Lonetto · Collegeville, US
• John Edward Hodgson · Malvern, US
• Richard Oakley Nicholas · Collegeville, US
• Leslie Marie Palmer · Audubon, US
• Julie M Pratt · Wigston, GB

Key dates

• Filing date: Mar 19, 1999
• Grant date: May 29, 2001
• Expiry date: Mar 19, 2019

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K48/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

This invention provides frr polypeptides and polynucleotides encoding frr polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing frr polypeptides to screen for antibacterial compounds.