Use of a non-mammalian DNA virus to express an exogenous gene in a mammalian cell
US6238914A · kind A · utility
25Cited by
9References
96Claims
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Assignee
Inventor
Key dates
| Filing date | Nov 19, 1996 |
| Grant date | May 29, 2001 |
| Priority date | — |
| Expiry date | Nov 19, 2016 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2710/14143
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Disclosed is a method of expressing an exogenous gene in a mammalian cell, involving infecting the cell with a non-mammalian virus (e.g., a baculovirus) whose genome carries an exogenous gene, and growing the cell under conditions such that the gene is expressed. Also disclosed is a method of treating a gene deficiency disorder in a mammal by providing to a cell a therapeutically effective amount of a virus whose genome carries an exogenous gene and growing the cell under conditions such that the exogenous gene is expressed in the mammal.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.