Nucleoside analogues
US6239159A · kind A · utility
119Cited by
0References
12Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 3, 1999 |
| Grant date | May 29, 2001 |
| Priority date | — |
| Expiry date | May 3, 2019 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07H19/056
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Nucleoside analogues in which a group M replaces the natural base where M is (1) or (2) or (3), where each of X.sup.1, X.sup.2 and X.sup.3 are C or N, each of R.sup.6 and R.sup.7 is the same or different and each is H, NO.sub.2, CO, COR.sup.8, OR.sup.8, CN, O, CON(R.sup.8).sub.2, COOR.sup.8, SO.sub.2 R.sup.8, SO.sub.3 R.sup.8, SR.sup.8, NHCHO, (CH.sub.2).sub.n (R.sup.8).sub.2, halogen, or a reporter moiety, each of R.sup.8 and R.sup.9 is H or hydrocarbyl or a reporter moiety, and n is 0-4. The analogues are substrates for polymerase and terminal transferase enzymes. ##STR1##
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.