Patent · US Expired

Method and compositions for inhibition of adaptor protein/tyrosine kinase interactions

US6239161A · kind A · utility

46Cited by
0References
9Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMay 5, 2000
Grant dateMay 29, 2001
Priority date
Expiry dateMay 5, 2020

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D209/14
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention relates to methods and compositions for the inhibition of adaptor protein/protein tyrosine kinase protein interactions, especially wherein those interactions involving a protein tyrosine kinase capable of complexing with a member of the SH2-and/or SH3-containing family of adaptor proteins are associated with a cell proliferative disorder. Specifically, the present invention relates to particular compounds, especially quinazoline derivative compounds, and methods utilizing such compounds.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.