Method and compositions for inhibition of adaptor protein/tyrosine kinase interactions
US6239161A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | May 5, 2000 |
| Grant date | May 29, 2001 |
| Priority date | — |
| Expiry date | May 5, 2020 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D209/14
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to methods and compositions for the inhibition of adaptor protein/protein tyrosine kinase protein interactions, especially wherein those interactions involving a protein tyrosine kinase capable of complexing with a member of the SH2-and/or SH3-containing family of adaptor proteins are associated with a cell proliferative disorder. Specifically, the present invention relates to particular compounds, especially quinazoline derivative compounds, and methods utilizing such compounds.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.