Non-steroidal polycyclic ring sulphamate derivatives, their preparation and their use as oestrone sulphatase inhibitors
US6239169A · kind A · utility
4Cited by
3References
6Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Aug 14, 1998 |
| Grant date | May 29, 2001 |
| Priority date | — |
| Expiry date | Aug 14, 2018 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A non-steroidal compound suitable for use as an inhibitor of oestrone sulphatase. The compound has a polycyclic ring structure comprising two or more rings wherein at least two of the rings mimic the A and B rings of oestrone. The compound can have the general formula A wherein R.sub.1 -R.sub.6 are independently selected from H, halo, hydroxy, sulphamate, alkyl and substituted variants or salts thereof; but wherein at least one of R.sub.1 -R.sub.6 is a sulphamate group; and wherein X is any one of O, S, NH, a substituted N, CH.sub.2 or a substituted C.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.