Pasteurized, purified von Willebrand factor concentrate and a process for the preparation thereof

US6239261A · kind A · utility

Assignee

• Aventis Behring GmbH · DE

Inventors

• Norbert Heimburger
• Gerhard Kumpe · Wetter, DE
• Klaus Wellner · Marburg, DE

Key dates

• Filing date: Jun 2, 1994
• Grant date: May 29, 2001
• Expiry date: Jun 2, 2014

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K14/755
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

A process for the preparation of a concentrate of von Willebrand factor is described, entailing a solution of a complex of this factor with factor VIII:C being optionally pasteurized and treated with an anion exchanger, there being no binding of the von Willebrand factor.