Patent · US Expired

Composition of S-sodium ibuprofen

US6242000A · kind A · utility

2Cited by

29References

23Claims

0Family size

Assignee

THE BOOTS COMPANY PLC · GB

Inventors

Bernard John Armitage
John F. Lampard · Mansfield, GB
Alan Smith · Grafton, GB

Key dates

Filing date	Oct 2, 1997
Grant date	Jun 5, 2001
Priority date	—
Expiry date	Oct 2, 2017

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07C57/30
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The use of S(-)sodium 2-(4-isobutylphenyl)propionate (the sodium salt of S(+)-ibuprofen) in pharmaceutical compositions for the treatment of inflammation, pain and pyrexia is described. Preferred compositions comprise S(-)sodium 2-(4-isobutylphenyl)propionate dihydrate. Processes to prepare S(-)sodium 2-(4-isobutyl-phenyl)propionate and its use in a process to prepare S(+) 2-(4-isobutylphenyl)propionic acid of high enantiomeric purity are also described.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.