Methods and means relating to retrotransposon and retroviral integration
US6242175A · kind A · utility
1Cited by
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15Claims
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Key dates
| Filing date | Jul 12, 1999 |
| Grant date | Jun 5, 2001 |
| Priority date | — |
| Expiry date | Jul 12, 2019 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/912
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Ku(Ku70 and Ku80) of yeast and mammalian cells and other components of the Ku-associated DNA repair pathway are involved in retrotransposon and retroviral integration into cellular nucleic acids. Agents which inhibit activity of the pathway are useful for inhibition of retroviruses. Such agents are obtainable using assays involving the Ku-associated DNA repair pathway and one or more components thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.