Methods and pharmaceutical compositions for inhibiting tumor cell growth
US6242196A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Sep 17, 1999 |
| Grant date | Jun 5, 2001 |
| Priority date | — |
| Expiry date | Sep 17, 2019 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K31/426
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method for inhibiting proliferation of a P.gamma.-responsive hyperproliferative cell which comprises the step of contacting the cell with (I) an inhibitory amount of a PPAR.gamma. agonist and (II) a MAP kinase inhibitor is disclosed. A method for treating or prophylactically preventing in an animal subject a disorder characterized by unwanted proliferation of PPAR.gamma.-responsive hyperproliferative cells which comprises administering to the subject (I) an inhibitory amount of a PPAR.gamma. agonist and (II) a MAP kinase inhibitor is also disclosed. Pharmaceutical compositions comprising a therapeutically effective amount of a PPAR.gamma. agonist and a MAP kinase inhibitor are disclosed for use in the methods.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.