Self-assembled metal colloid monolayers having size and density gradients
US6242264A · kind A · utility
48Cited by
7References
13Claims
0Family size
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Key dates
| Filing date | Jan 12, 2000 |
| Grant date | Jun 5, 2001 |
| Priority date | — |
| Expiry date | Jan 12, 2020 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T436/196666
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A biosensor based on complexes between biomolecule receptors and colloidal Au nanoparticles, and more specifically, colloid layers of receptor/Au complexes that can be used to detect biomolecule analytes through measuring of binding-induced changes in electrical resistance or surface plasmon resonance. Also disclosed is a method for detecting and analysing carrier-borne chemical compounds with Raman spectroscopy using an improved SERS substrate. Further disclosed is an improved method for detecting compounds in solvents using capillary electrophoresis in conjunction with Raman spectroscopy.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.