Single isomer methylphenidate and resolution process
US6242464A · kind A · utility
11Cited by
3References
2Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jan 22, 1997 |
| Grant date | Jun 5, 2001 |
| Priority date | — |
| Expiry date | Jan 22, 2017 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D211/34
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Single isomer methylphenidate, selected from the d- and l-threo-enantiomers, has been obtained in purified form, to the extent of less than 2% by weight of a contaminant selected from resolving agent and ritalinic acid. This is achieved by resolution of a mixture of enantiomers using an O,O'-diaroyltartaric acid as resolving agent.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.