Five member ring sulfenate esters and thiosulfinate esters
US6242478A · kind A · utility
2Cited by
0References
58Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 10, 1999 |
| Grant date | Jun 5, 2001 |
| Priority date | — |
| Expiry date | Dec 10, 2019 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D339/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Disclosed are novel sulfenate esters and thiosulfinate esters that induce the expression of metabolic enzymes, particularly Phase II enzymes such as glutathione-s-transferase, DT-diaphorase and Ferritin H when administered to a subject. Also disclosed, such compounds are effective to displace a zinc ion from retroviral zinc finger nucleocapsid proteins effective to inhibit HIV replication. The present invention is further directed to novel methods of making these compounds, and any compounds produced by the process of making these novel compounds.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.