Selectively cytotoxic acetogenin compounds
US6242483A · kind A · utility
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4Claims
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Key dates
| Filing date | Dec 15, 1999 |
| Grant date | Jun 5, 2001 |
| Priority date | — |
| Expiry date | Dec 15, 2019 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D307/58
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The isolation of three new mono-tetrahydrofuran ring acetogenins from the bark of Annona squamosa is described. Each of these compounds bears a carbonyl group at the C-9 position and two hydroxyls that flank the tetrahydrofuran ring. These compounds exibit selective cytotoxic activity against certain specific human tumor cells.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.