Indolyl neuropeptide Y receptor antagonists

US6245761A · kind A · utility

Assignee

• ELI LILLY AND COMPANY · US

Inventors

• Thomas C. Britton · Carmel, US
• Robert F. Bruns, Jr. · Ann Arbor, US
• Donald R. Gehlert · Indianapolis, US
• Philip Arthur Hipskind · New Palestine, US
• Karen L. Lobb · Indianapolis, US
• James A. Nixon · Indianapolis, US
• Paul Leslie Ornstein · Carmel, US
• Edward C. R. Smith · Fishers, US
• Hamideh Zarrinmayeh · Carmel, US
• Dennis M. Zimmerman · Mooresville, US

Key dates

• Filing date: Aug 29, 1996
• Grant date: Jun 12, 2001
• Expiry date: Aug 29, 2016

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D453/02
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

This invention provides a series of substituted indoles which are useful in treating or preventing a condition associated with an excess of neuropeptide Y. This invention also provides the novel substituted indoles as well as pharmaceutical formulations with comprise as an active ingredient one or more of these substituted indoles.