Anti-flammatory carbohydrate binding-peptides
US6245883A · kind A · utility
2Cited by
23References
28Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 9, 1998 |
| Grant date | Jun 12, 2001 |
| Priority date | — |
| Expiry date | Sep 9, 2018 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S530/868
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention is directed to lectin derived carbohydrate binding peptides or derivatives thereof useful for suppressing inflammatory responses, inducing tolerance to an antigen, and suppressing cell adhesion, e.g., involved in metastasis. In particular, peptides capable of binding terminally linked .alpha.-sialic acid(2-6).beta.Gal- and/or .alpha.-sialic acid(2-3).beta.Gal-groups on structures or molecules comprising such groups are provided. Pharmaceutical compositions containing such lectin derived carbohydrate binding peptides are also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.