Monoclonal antibodies that recognize antigens associated with tumor metastasis
US6245898A · kind A · utility
10Cited by
2References
19Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 15, 1999 |
| Grant date | Jun 12, 2001 |
| Priority date | — |
| Expiry date | Jun 15, 2019 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2039/505
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This invention provides tumor metastasis-inhibiting monoclonal antibodies, mAb 41-2, mAb 50-6 and mAb 1A-5. The antigen recognized by mAb 50-6 and mAb 1A-5 has been identified as the PETA-3 antigen. The antigen recognized by mAb 41-2 has been identified as a novel tumor metastasis-associated antigen. Compositions and methods are provided that are useful for treating and diagnosing metastatic tumors.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.