Azithromycin monohydrate isopropanol clathrate and methods for the manufacture thereof
US6245903A · kind A · utility
24Cited by
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9Claims
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Key dates
| Filing date | Aug 13, 1999 |
| Grant date | Jun 12, 2001 |
| Priority date | — |
| Expiry date | Aug 13, 2019 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07H17/08
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A novel form of azithromycin and processes for preparation of pure azithromycin monohydrate isopropanol clathrate (3 molecules of isopropanol for every 10 molecules of azithromycin monohydrate) has been obtained. Preparation of the novel form of azithromycin comprises the steps of dissolving azithromycin in isopropanol, followed by the slow addition of water to the organic solution.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.