Cascade polymer complexes, process for their production and pharmaceutical agents containing said complexes

US6248306A · kind A · utility

Assignee

• SCHERING CORPORATION · US

Inventors

• Heribert Schmitt-Willich · Berlin, DE
• Johannes Platzek · Berlin, DE
• Ulrich Niedballa · Berlin, DE
• Bernd Raduchel · Berlin, DE
• Andreas Muhler · Oderberg, DE
• Thomas Frenzel · Berlin, DE
• Wolfgang Ebert · Krefeld, DE

Key dates

• Filing date: Jun 6, 1995
• Grant date: Jun 19, 2001
• Expiry date: Jun 6, 2015

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y10S424/16
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Cascade polymer complexes containing PA1 a) complexing ligands of general formula I EQU A--{X--[Y--(Z--( W--K.sub.w).sub.z).sub.y ].sub.x }.sub.a (I) PA1 in which PA2 A stands for a nitrogen-containing cascade nucleus of base multiplicity a, PA2 X and Y, independently of one another, stand for a direct bond or a cascade reproduction unit of reproduction multiplicity x or y, PA2 Z and W, independently of one another, stand for a cascade reproduction unit of reproduction multiplicity z or w, PA2 K stands for the radical of a complexing agent, PA2 a stands for numbers 2 to 12, PA2 x, y, z and w, independently of one another, stand for numbers 1 to 4, provided that at least two reproduction units are different and that EQU 16.ltoreq.a.multidot.x.multidot.y.multidot.z.multidot.w.ltoreq.64 holds true for the product of the multiplicities, PA1 b) at least 16 ions of an element of atomic numbers 20 to 29, 39, 42, 44 or 57-83 and PA1 c) optionally cations of inorganic and/or organic bases, amino acids or amino acid amides are valuable compounds for diagnosis and therapy.