Modulation of endothelial cell surface receptor activity in the regulation of angiogenesis
US6248327A · kind A · utility
7Cited by
8References
22Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 11, 1998 |
| Grant date | Jun 19, 2001 |
| Priority date | — |
| Expiry date | Sep 11, 2018 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K16/40
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method of modulating angiogenesis in a vertebrate subject, the method comprising administering to the vertebrate subject an ECRTP/DEP-1 receptor activity-modulating amount of a composition, whereby an ECRTP/DEP-1 receptor within the vertebrate subject is contacted by the composition; and modulating angiogenesis through the contacting of the ECRTP/DEP-1 receptor with the composition. Optionally, the composition includes a monoclonal antibody which preferentially binds the ECRTP/DEP-1 receptor.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.