Prolonged anesthesia in joints and body spaces

US6248345A · kind A · utility

Assignee

• Euro-Celtique S.A. · LU

Inventors

• Paul Goldenheim · Wilson, US
• Peter Lacouture · Coventry, US
• Donna Donigi-Gale · Trumbull, US
• Mark Chasin · Manalapan, US
• Richard Sackler · Greenwich, US

Key dates

• Filing date: Jul 2, 1998
• Grant date: Jun 19, 2001
• Expiry date: Jul 2, 2018

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y10T428/2982
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Sustained release local anesthetic formulations are administered intra articularly and/or into body spaces/cavities. The formulation is preferably a plurality of injectable microparticles including a local anesthetic and an effective amount of a biocompatible, biodegradable, sustained release material prolonging the release of the local anesthetic and optionally and a pharmaceutically acceptable, i.e., non-toxic, augmenting agent effective to prolong the duration of the local anesthesia for a time period longer than that obtainable without the augmenting agent.