Patent · US Expired

Isoquinolines as urokinase inhibitors

US6248738A · kind A · utility

11Cited by
0References
27Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMay 30, 2000
Grant dateJun 19, 2001
Priority date
Expiry dateMay 30, 2020

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D491/04
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

Compounds of formula (I): ##STR1## and pharmaceutically acceptable salts thereof, wherein one of R.sup.1 and R.sup.2 is H and the other is N.dbd.C(NH.sub.2).sub.2 or NHC(.dbd.NH)NH.sub.2, and the other substituents are as defined herein, are urokinase (uPA) inhibitors.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.