Treatment of inflammation with 2,4,6-trihydroxy-alpha-rho-methoxyphenylacetophenone, or its pharmaceutically acceptable derivatives
US6248790A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jun 29, 2000 |
| Grant date | Jun 19, 2001 |
| Priority date | — |
| Expiry date | Jun 29, 2020 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K31/12
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
2,4,6-trihydroxy-.alpha.-p-methoxyphenylacetophenone (also identified herein as "D-58"), or its pharmaceutically acceptable derivatives such as salt and ester forms, is administered for inhibiting inflammatory reactions. The treatment can be remedial or prophylactic. Examples of the conditions that can be treated include acute inflammatory reactions and allergic inflammatory reactions, and specific examples include allergy, asthma, arthritis, psoriasis, skin sunburn, inflammatory pelvic disease, inflammatory bowel disease, urethritis, uvitis, senusitis, pneumonitis, encephalitis, meningitis, myocarditis, nephritis, osteomyelitis, myositis, hepatitis, gastritis, enteritis, dermatitis, gingivitis, appendicitis, pancreatitis, cholocystitis and cholangitis. The 2,4,6-trihydroxy-.alpha.-p-methoxyphenylacetophenone can be administered by various routes as needed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.