Water insoluble polymer based sustained release formulation
US6251430A · kind A · utility
Inventors
Key dates
| Filing date | Feb 4, 1998 |
| Grant date | Jun 26, 2001 |
| Priority date | — |
| Expiry date | Feb 4, 2018 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K9/2054
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Sustained release drug formulations contain the pharmaceutical itself and a three component release rate controlling matrix composition. The three components of the matrix composition are (1) water insoluble polymer, such as ethyl cellulose, (2) pH dependent gelling polymer, such as sodium alginate, and (3) a pH independent gelling polymer, such as hydroxypropyl methylcellulose. The drug release rate can be adjusted by changing the amount of one or more of these components of the composition.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.