Hydroxyindoles, their use as inhibitors of phosphodiesterase 4 and process for their preparation

US6251923A · kind A · utility

Assignee

• Arzneimittelwerk Dresden GmbH · DE

Inventors

• Norbert Höfgen · Radeberg, DE
• Ute Egerland · Radebeul, DE
• Hildegard Poppe · Dresden, DE
• Degenhard Marx · Radebeul, DE
• Stefan Szelenyi · Arnstorf, DE
• Thomas Kronbach · Radebeul, DE
• Emmanuel Polymeropoulos · Frankfurt, DE
• Sabine Heer · Radebeul, DE

Key dates

• Filing date: Apr 28, 1999
• Grant date: Jun 26, 2001
• Expiry date: Apr 28, 2019

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D401/12
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention relates to new hydroxyindoles of the Formula, ##STR1## their use as inhibitors of phosphodiesterase 4 and processes for their preparation.