Treatment of migraine by administration of .alpha.-lipoic acid or derivatives thereof

US6251935A · kind A · utility

Assignee

• Asta Medica Aktiengesellschaft · DE

Inventors

• Jean Schoenen · Chaudfontaine, BE
• Jurgen Engel · Alzenau, DE
• Klaus Wessel · Frankfurt, DE
• Manfred Peukert · Warstein, DE
• Michael Lobisch · Ober-Ramstadt, DE
• Harald Borbe · Mainz, DE

Key dates

• Filing date: Aug 15, 2000
• Grant date: Jun 26, 2001
• Expiry date: Aug 15, 2020

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P43/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention relates to the use of racemic .alpha.-lipoic acid or its enantiomers or pharmaceutically acceptable salts, amides, esters or thioesters thereof, in reduced or oxidized form, as active ingredient in the prevention or the acute or chronic treatment of migraine.