Transgenic mammal having 5-HT3 transgene overexpression in the CMS
US6252131A · kind A · utility
1Cited by
1References
12Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 15, 1998 |
| Grant date | Jun 26, 2001 |
| Priority date | — |
| Expiry date | Oct 15, 2018 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA01K2267/03
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The invention relates to transgenic mammals characterized by 5-HT.sub.3 receptor over-expression in the central nervous system (CNS) . The mammals have particular utility as models for studying the role of 5-HT.sub.3 receptors in the CNS, especially for the study of reward pathways for alcohol and other substances of abuse.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.