Polymorphism of the human GluR-5 gene and risk factor for alzheimer disease
US6255054A · kind A · utility
7Cited by
2References
8Claims
0Family size
Inventors
Key dates
| Filing date | Sep 9, 1999 |
| Grant date | Jul 3, 2001 |
| Priority date | — |
| Expiry date | Sep 9, 2019 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2600/156
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention concerns a method and kit for determining if a subject is at increased or decreased risk of developing Alzheimer's disease. The invention further concerns vectors, transformed cells or transgenic mammals which can be used in a method for the screening of compound capable of modulating the expression of the GluR-5 gene or the activity of the GluR-5 receptor. The compounds selected by the method of the invention, as medicament for the treatment or the prevention of Alzheimer's disease, also form part of the present invention.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.