Benzimidzolyl neuropeptide Y receptor antagonists

US6255494A · kind A · utility

Assignee

• ELI LILLY AND COMPANY · US

Inventors

• Thomas C. Britton · Carmel, US
• Robert F. Bruns, Jr. · Ann Arbor, US
• Buddy Eugene Cantrell · Fountaintown, US
• Philip Arthur Hipskind · New Palestine, US
• Karen L. Lobb · Indianapolis, US
• James A. Nixon · Indianapolis, US
• Paul Leslie Ornstein · Carmel, US
• Edward C. R. Smith · Fishers, US
• Hamideh Zarrinmayeh · Carmel, US
• Dennis M. Zimmerman · Mooresville, US
• Anne Marie Nunes · Andover, US
• James Jeffry Howbert · Bellevue, US

Key dates

• Filing date: Jan 9, 1997
• Grant date: Jul 3, 2001
• Expiry date: Jan 9, 2017

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D417/14
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

This invention provides a series of substituted benzimidazoles which are useful in treating or preventing a condition associated with an excess of neuropeptide Y. This invention also provides methods employing these substituted benzimidazoles as well as pharmaceutical formulations with comprise as an active ingredient one or more of these compounds.