Purified sperm surface antigen, monoclonal antibody therefor and application therefor
US6258364A · kind A · utility
4Cited by
0References
2Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 23, 1998 |
| Grant date | Jul 10, 2001 |
| Priority date | — |
| Expiry date | Feb 23, 2018 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2800/367
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
S19 mAb, deposited under Accession Number HB-12144 at the ATCC, binds to a carbohydrate epitope of a glycoprotein found distributed over the surface of sperm. The carbohydrate nature of the epitope, its distribution over the entire sperm surface, and the fact that it is epididymal/sperm specific and not naturally found in any of the tissues of the female reproductive tract, make the glycoprotein, SAGA-1, a desirable immunogen as the active agent for a contraceptive vaccine, as well as a test standard for monitoring antibody titer. The antibody provides a diagnostic for the presence of sperm, as well as a topical spermistatic.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.